Parthenolide inhibits TRIF-dependent signaling pathway of toll-like receptors in RAW264.7 macrophages
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چکیده
منابع مشابه
Suppression of the TRIF-dependent signaling pathway of Toll-like receptors by luteolin.
Toll-like receptors (TLRs) play important roles in induction of innate immune responses for both host defense against invading pathogens and wound healing after tissue injury. Since dysregulation of TLR-mediated immune responses is closely linked to many chronic diseases, modulation of TLR activation by small molecules may have therapeutic potential against such diseases. Expression of the majo...
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Objective(s): To explore whether endoplasmic reticulum (ER) stress regulates inflammation in adipose tissue of obese rats via TLR4 signaling. Materials and Methods: Sprague Dawley rats were randomly divided into four groups, and body weight, food intake, and free fatty acids (FFA) were measured. Real-time PCR and Western blot were used to determine mRNA or protein expression of TLR4, TRAF6, IKK...
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ژورنال
عنوان ژورنال: Molecules and Cells
سال: 2011
ISSN: 1016-8478,0219-1032
DOI: 10.1007/s10059-011-0032-8